So, the FDA is rolling out an anti-obesity drug. Which got denied, but the mere proposal of it made my blood boil.
Take a close look at the article and note the ingredients: phentermine and topiramate. Now, I know phentermine is an effective weight-loss drug, but combining it with what’s basically Topamax is a very fucking bad idea.
Per drugs.com, topiramate is a seizure medication, which is sometimes used to treat migraines in adults. The reason that it makes for a great addition here is because it’s an appetite suppressant. While that’s so, it doesn’t take away the fact that this will, invariably, be altering the way that a person’s brain functions.
Also, who remembers the Fen-Phen lawsuits? And that the drug was known to cause pulmonary hypertension? Phentermine is a stimulant and appetite suppressant as well, already marketed as an anti-obesity drug, and it’s an ingredient in this mix as well. It’s also of a composition similar to amphetamine. In fact, it’s a controlled Schedule IV Substance.
Now, think about it. I’m not a pharmacist, but I do have this thing called logic. So, in this exercise, we’re taking a drug that is commonly used to treat migraines and seizures, which by reason of logic, will temporarily alter the way that the brain functions, and using it in order to tank appetite. We’re then adding an amphetamine-style stimulant.
Does anyone else see a recipe for disaster?
I certainly do. If Fen-Phen caused abnormal valve findings in addition to pulmonary hypertension when combined with fenfluramine, I don’t see good things coming out of this combination. You already have something that alters brain function, temporarily (long enough to relieve a headache? Or control small seizures?), and then you’re adding an amph-style drug into the mix. Bad? YES.
Amazing. To risk people’s lives because of a perceived epidemic which isn’t an epidemic at all. Lovely. How long before the lawsuits for this one begin?
To quote the illustrious folks at Merriam-Webster:
Definition of EPIDEMIC